Organic chemistry
Reactions from organic chemistry 1 and 2 with reagent, product and mechanism: for chemistry, biochemistry, pharmacy and medicine. Every reaction has its own page to look up and practise.
Organic chemistry trainerNew problems every day, no sign-upSpectroscopy trainerNew problems every day, no sign-up
Nucleophilic substitution
SN2 with hydroxideSN2 with cyanide (chain extension)SN2 with ammoniaWilliamson ether synthesisSN1 (hydrolysis)SN1 (solvolysis in ethanol)Finkelstein reactionRadical bromination of alkanesSN2 with azideEpoxide opening under basic conditionsEpoxide opening under acidic conditionsEther cleavage with HI
Elimination
Alkenes & alkynes
Pericyclic reactions
Alcohols
Carbonyl chemistry
Carboxylic acids & derivatives
Acyl chloride from carboxylic acidFischer esterificationEster hydrolysis (saponification)Amide from acyl chlorideEster from acyl chlorideAcidic hydrolysis of amides and nitrilesAcylation of aminesReduction with DIBAL-HTransesterificationEsterification with acetic anhydrideBeckmann rearrangementKetone from acid chloride and cuprate
Aromatic compounds
Enolates & condensations
Michael additionRobinson annulationClaisen condensationDieckmann condensationMalonic ester synthesisAcetoacetic ester synthesisAlkylation with LDA (kinetic enolate)α-Bromination of ketones (acidic)Hell–Volhard–Zelinsky reactionMannich reactionDecarboxylation of β-keto acidsIntramolecular aldol condensation
Amines
Carbohydrates
Amino acids & peptides
Heterocycles
Paal–Knorr synthesis (pyrrole)Paal–Knorr synthesis (furan)Paal–Knorr synthesis (thiophene)Acylation of furan, thiophene and pyrroleVilsmeier–Haack formylationElectrophilic substitution of pyridineChichibabin reactionNucleophilic substitution of halopyridinesPyridine N-oxideN-alkylation of pyridineFischer indole synthesis